A new genetic test for one of the most common forms of breast cancer will help doctors better identify those women who should be considered for chemotherapy, and those who can avoid it, say researchers. A team at The Institute of Cancer Research, London, The Royal Marsden NHS Foundation Trust...
More Women Should Receive Intraperitoneal Treatment, Suggests 10-Year Follow-up Patients with advanced ovarian cancer who undergo intensive treatment with chemotherapy that bathes the abdomen are significantly more likely to live longer than those who receive standard intravenous (IV)...
Diem Brown is battling ovarian cancer for the second time in her twenties–and very publicly. She's keeping a blog about her experience and treatment over at People, and today she posted photos from a photo shoot that reveals her hair loss from chemotherapy–something she has mixed emotions about...
In a world-first, researchers from the Australian Centre for Nanomedicine at the University of New South Wales (UNSW) in Sydney have developed a nanoparticle that could improve the effectiveness of chemotherapy for neuroblastoma by a factor of five. Neuroblastoma is an aggressive childhood...
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene by Philippe Roux, a researcher at the University of Montreal's Institute for Research in Immunology and Cancer (IRIC). "Our findings reveal part of the...
According to a study published Online First in The Lancet Oncology, babies born to women with breast cancer who received chemotherapy while pregnant do not seem to be at greater risk of complications. The researchers analyzed over 400 women from across Europe who had been identified as having...
Researchers at Washington University School of Medicine in St. Louis have shown how an aggressive form of multiple myeloma resists chemotherapy. Multiple myeloma is a rare cancer of plasma cells in the bone marrow. Though the finding has no immediate benefit for patients, the scientists say it...
The antidepressant drug duloxetine, known commercially as Cymbalta, helped relieve painful tingling feelings caused by chemotherapy in 59 percent of patients, a new study finds. This is the first clinical trial to find an effective treatment for this pain. Chemotherapy-induced peripheral...
Chemotherapy is a major first line defense against breast cancer. However a patient's response is often variable and unpredictable. A study published in BioMed Central's open access journal BMC Medical Genomics shows that 'gene expression signatures' for TOP2A and β-tubulin can be used to...
Genetic mutations in cancer cells can lead to resistance to treatment, thereby potentially resulting in relapse. However, a new article, published in the magazine section of the online, open-access journal PLoS Biology, suggests that the converse may also happen. Steven Frank from the University...
A large, retrospective study shows that children of childhood cancer survivors who received prior treatment involving radiation to testes or ovaries and/or chemotherapy with alkylating agents do not have an increased risk for birth defects compared to children of survivors who did not have such...
Challenging a half-century-old theory about why chemotherapy agents target cancer, scientists at Dana-Farber Cancer Institute have devised a test that can predict how effective the drugs will be by determining whether a patient's tumor cells are already "primed" for death. In a study published...
Johns Hopkins researchers have devised a protein "switch" that instructs cancer cells to produce their own anti-cancer medication. In lab tests, the researchers showed that these switches, working from inside the cells, can activate a powerful cell-killing drug when the device detects a marker...
Patients receiving virtually all types of chemotherapy have been advised not to take fish oil supplements because they can make chemotherapy drugs ineffective, researchers from the University Medical Centre Utrecht, the Netherlands wrote in the journal Cancer Cell. Fish oils contain two fatty...
Researchers of the University of Granada and Edimbourgh have developed a new therapy for cancer based on nanotechnology that might improve significantly chemotherapy, as it has not cause side effects. This therapy is based on the encapsulation of a catalyst (palladium) into microspheres, to...
The use of trastuzumab, chemotherapy and surgery among women with HER2-positive metastatic breast cancer significantly improved survival from the time central nervous system metastases were diagnosed. Based on these study results, lead researcher Adam Brufsky, M.D., Ph.D., said, "We clearly now...
Sanofi (EURONEXT: SAN and NYSE: SNY) announced today results of the pivotal SAVE-ONCO study which demonstrated that, in cancer patients initiating a chemotherapy regimen, investigational semuloparin significantly reduced the risk of the composite of symptomatic-deep vein thromboembolism (DVT)...
Although chemotherapy is used to kill cancer cells, it can also have a strong toxic effect on normal cells such as bone marrow and blood cells, often limiting the ability to use and manage the chemotherapy treatment. Researchers at Fred Hutchinson Cancer Research Center reported at the annual...
Ipilimumab used in combination with paclitaxel/carboplatin for stage IIIb/IV non-small cell lung cancer showed superior results in progression free survival when compared to paclitaxel/carboplatin alone, according to research presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic...
Genta Incorporated (OTCBB: GETA.OB) announced preliminary results that show a high objective response rate in a pilot study of patients with advanced melanoma that incorporates the Company's lead oncology product, Genasense® (oblimersen sodium) Injection, administered for the first time as a...