Nearly two-thirds of patients with high-risk neuroblastoma - a common tumor that forms in the nerve cells of children - cannot be cured using tumor-killing cancer drugs. A study published by Cell Press in the journal Chemistry & Biology reveals a new genomic approach to screen for compounds that...
Targeted cancer therapy has been transforming the care of patients with non-small-cell lung cancer (NSCLC). It is now standard practice for tumor specimens from NSCLC patients to be examined for EGFR mutations and ALK rearrangements to identify patients for therapy with EGFR and ALK inhibitors...
Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according to a presentation at the American Society of Human Genetics 2012...
In the early stages of that vast undertaking known as the Human Genome Project, enthusiasm ran high. The enterprise would be costly and laborious but the clinical rewards, unprecedented. Once the complete blueprint of life was unlocked, the genetic underpinnings for a broad range of human...
Genetically, culturally and ethically the Khoe-San have something special to add to this world. The importance of this study is to put the Khoe and San heritage in the right place in history and this research will provide a genetic backdrop for future studies - Mattias Jakobsson. The largest...
People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The findings, published online in the journal Nature...
Using a diversity of DNA sequencing and human genome analytic techniques, researchers led by Baylor College of Medicine have identified some cases of developmental delay or cognitive disorders associated with a sudden chromosomal catastrophe that occurred early in development, perhaps during...
FDA scientists successfully used a new genome sequencing test to retrospectively examine a 2009-2010 foodborne illness outbreak to help trace the source of the infection. A Salmonella Montevideo outbreak that began early in 2010 was linked to spice rubs on certain salamis and sickened nearly 300...
Genomic Health, Inc. (Nasdaq: GHDX) announced that the company will present results from seven studies at the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium (SABCS), taking place December 8-12, 2010 at the Henry B. Gonzalez Convention Center. All of the studies analyze the company's...
Obesity is highly heritable, but so far genetic association studies have only explained a small fraction of this heritability. Now, in a study published in BioMed Central's open access journal Genome Biology, researchers have identified DNA variants in two nervous system genes that are...
Apart from cutaneous malignancies, prostate cancer (CaP) still remains the most common cancer in men. However, the pathophysiology underlying the disease remains poorly understood and no definite behavioral or environmental risk factors have been identified. Genetics is an important, and...
Scientists can gain insights into new ways to use microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems, according to a new report from the American Academy of Microbiology that...
Scientists can gain insights into new ways to use microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems, according to a new report from the American Academy of Microbiology that...
Scientists can gain insights into new ways to use microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems, according to a new report from the American Academy of Microbiology that...
Scientists can gain insights into new ways to use microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems, according to a new report from the American Academy of Microbiology that...
Scientists can gain insights into new ways to use microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems, according to a new report from the American Academy of Microbiology that...