Glycotope GmbH, a global leader in optimizing the sugar chains (glycosylation) of biopharmaceuticals, announced full details of first-in-man Phase I trial data for CetuGEXTM, an anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) with optimized and fully human glycosylation...
Approximately a year ago, the leading journal Science published an article about bexarotene as a potential Alzheimer’s drug. A significant breakthrough and an important starting point for further Alzheimer’s research.
The research group of Bart De Strooper*– Alzheimer’s researcher at VIB and...
An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report. The treatment, developed at Duke and tested in an ongoing phase 1 study, capitalizes on...
CDC papers discuss the potential roles of social and family networks, media, and lawmakers in efforts to prevent skin cancer by reducing use of indoor tanning devices, American Journal of Preventive Medicine reports Preventing skin cancer by reducing use of indoor tanning devices requires a...
A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future. Described in...
A new study shows that a microbicide gel is highly effective in block infection by the AIDS virus in a non-human primate model. In the paper published December 6 in the Open Access journal PLOS Pathogens, Dereuddre-Bosquet and colleagues from the European Combined Highly Active Anti-Retroviral...
There's new hope in the fight against Huntington's disease. A group of researchers that includes scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have designed a compound that suppresses symptoms of the devastating disease in mice. The compound...
A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial. "The bold long-term goal is a short-term oral treatment that prevents breast cancer by killing the precursor cells that initiate breast cancer," says Lance...
"Addiction is a brain disease" was the title of an editorial in the renowned journal Science 15 years ago. The author argued that recognising addiction as a disorder of the brain can impact society´s overall health and social policy strategies and help diminish the health and social costs...
A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options. Melanoma patients have...
Studies have shown that declines in temporal information processing (TIP), the rate at which auditory information is processed, underlies the progressive loss of function across several cognitive systems in elderly people. This includes problem solving, new learning, thinking, attention, memory...
Yona Goldshmit, Ph.D., is a former physical therapist who worked in rehabilitation centers with spinal cord injury patients for many years before deciding to switch her focus to the underlying science. "After a few years in the clinic, I realized that we don't really know what's going on," she...
Researchers from the Perelman School of Medicine at the University of Pennsylvania have identified an abnormal amount a protein called Prostaglandin D2 in the bald scalp of men with male pattern baldness, a discovery that may lead directly to new treatments for the most common cause of hair loss...
The histamine releasing factor (HRF) molecule has been identified by researchers at La Jolla Institute for Allergy & Immunology, as a potential target for developing novel therapies for numerous allergic reactions, including asthma. The study is published online in the Journal of Clinical...
...into for the future ? I'm 18 and want to get into something sustainable that will help raise consciousness about what we are currently doing to the planet ... I know that in my lifetime things will be extremely ruff unless people gain self sufficiency and start living less materialistic and...
Kelly Clarkson on Dancing With the Stars next season? It probably won't happen, but Tom Bergeron was certainly persuasive as he assured tonight's first musical guest that, even...
A groundbreaking study in the journal Nature Medicine suggests what could become the first effective treatment for a debilitating and fatal disease of the central nervous system called SCA1. The study, based on an animal model, found that the disease is linked to low levels of a multipurpose...
For the first time, a malaria vaccine that uses the entire malaria parasite has proven safe and shown promise to produce a strong immune response in a clinical trial, according to a new study co-authored by researchers at the University of Maryland School of Medicine Center for Vaccine...
Half-matched bone marrow or stem cell transplants for blood cancer patients have typically been associated with disappointing clinical outcomes. However, a clinical trial conducted at the Kimmel Cancer Center at Jefferson testing its unique, two-step half-match procedure has produced some...
A University of Colorado School of Medicine scientist is completing a major clinical trial on a drug that could boost cognitive function in those with Down syndrome, significantly improving their quality of life and representing a potential milestone in research on this genetic condition. "We...