Two new studies by researchers at Hospital for Special Surgery have shed light on joint replacement outcomes in patients with rheumatoid arthritis (RA). One study overturns the common belief that RA patients have worse outcomes after a total knee replacement (TKR) than patients who undergo the...
A new study conducted in an ethnically diverse and predominantly low income population found that only one-fifth of rheumatoid arthritis (RA) patients had an overall adherence rate to prescribed oral medications at 80% or greater. Findings published in Arthritis & Rheumatism, a journal of the...
In a series of lab experiments designed to unravel the workings of a key enzyme widely considered a possible trigger of rheumatoid arthritis, researchers at Johns Hopkins have found that in the most severe cases of the disease, the immune system makes a unique subset of antibodies that have a...
Friday 12 October is "World Arthritis Day". Scientists affiliated with VIB and UGent have discovered a mechanism used by the protein A20 to combat inflammation. This could be a very important point of focus in the search for a treatment for autoimmune diseases such as Rheumatoid Arthritis, in...
Regenerative medicine company Mesoblast Limited (ASX:MSB) have announced positive results in a large animal model of Rheumatoid Arthritis (RA) following a single intravenous injection of its proprietary allogeneic, or "off-the-shelf", immunomodulatory adult Mesenchymal Precursor Cells (MPCs)...
Researchers from Austria have determined that patients with rheumatoid arthritis (RA) and their doctors differ on perception of RA disease activity. The study now available in Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR) and published by Wiley, reports that RA...
Data from one of the few head-to-head trials in rheumatoid arthritis (RA) presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism, demonstrates that at one year, 64.8% of patients receiving abatacept (Orencia) and 63.4% of patients receiving adalimumab (Humira)...
Over one million adults in the U.S. suffer from rheumatoid arthritis, a systemic inflammatory autoimmune disease that can be incapacitating. Researchers have now discovered the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). The study...
A bacterium historically associated with cat scratch fever and transmitted predominately by fleas may also play a role in human rheumatoid illnesses such as arthritis, according to new research from North Carolina State University. Bartonella is a bacterium that is maintained in nature by fleas...
Add lower gastrointestinal (GI) problems such as ulcers, bleeding and perforations to the list of serious complications facing many rheumatoid arthritis patients. They are at greater risk for GI problems and gastrointestinal-related death than people without the disease, a Mayo Clinic study...
Women under 50 with rheumatoid arthritis are at greater risk of breaking bones than women without the condition, according to a Mayo Clinic study being presented at the American College of Rheumatology annual scientific meeting in Chicago. Men with rheumatoid arthritis also are in more danger of...
Compared with osteoarthritis patients, individuals with rheumatoid arthritis who undergo total knee replacement surgery have lower expectations about their postsurgical outcomes, according to a new study by researchers at Hospital for Special Surgery (HSS) in New York City. These reduced...
As guidelines recommend, doctors appear to be stopping anti-TNF medications before surgery, but may be doing so far sooner than is necessary, according to a new study by researchers at Hospital for Special Surgery. These medications are used to treat a variety of inflammatory diseases, including...
Researchers from VIB (Flanders Institute for Biotechnology) and Ghent University have shown that a defective gene can contribute to the onset of rheumatoid arthritis, an often-crippling inflammation of the joints that afflicts about 1% of the world's population. Until now, the underlying...
Scientists at Mount Sinai Hospital, in collaboration with researchers at the University of Toronto, University Health Network and McGill University have obtained significant new insights into the causes of rheumatoid arthritis (RA) and other autoimmune disorders including type 1 diabetes, lupus...
Today the National Rheumatoid Arthritis Society (NRAS) has launched the NRAS Care Plan, a patient-held record designed to improve a patient's ability to self-manage their Rheumatoid Arthritis...
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The increasing use of biologic agents and of the disease-modifying drug methotrexate over the last decade has revolutionised the management of rheumatoid arthritis (RA). Today RA is much better controlled. In most cases disease activity can be suppressed when it flares, the terrible swan neck...
Tasocitinib (CP-690,550) has been found to reduce the signs and symptoms of rheumatoid arthritis considerably, as well as significantly improving physical function according to a Phase 3 clinical trial, ORAL Solo (1045), says Pfizer. Tasocitinib, used as a monotherapy - on its own - is an oral...
The American College of Rheumatology today announced the release of revised classification criteria (created in collaboration with the European League Against Rheumatism) for rheumatoid arthritis, which will allow the study of treatments for RA at much earlier stages of the disease - before...