5-Alpha reductase inhibitors (5-ARI), such as finasteride and dutasteride, may increase the specificity of the prostate-specific antigen (PSA) test in men with elevated or fluctuating PSA levels and previous negative biopsy, according to new data from researchers from NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City. Investigators postulate that PSA velocity while undergoing 5-ARI therapy can be a useful diagnostic adjunct for detection of prostate cancer...

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