Disruption Of Gene Used To Transport Proteins Leads To ALS

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A Purdue University biochemist has determined the function of a gene that when mutated leads to a genetic variation of amyotrophic lateral sclerosis, or Lou Gehrig's disease. James Clemens, an assistant professor of biochemistry, found that a gene called VAPB is responsible for transporting certain proteins to their proper places along neurons. When the gene is mutated or deleted, these proteins are unable to make it to locations in neurons where their function is critically required...
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