You certainly could! It would give you a few side effects though. With that size wheel even with the lowest profile tire, you'll have a larger outer diameter than the stock wheels, so your mileage will be off as well as your speedometer. To be honest I wouldn't go 22's anyways, but it's all up to you. If you're willing to give up all accuracy, use of speedometer, and handling since 22's will weigh a ton...go for it. Hope this helps.