The second-generation proteasome inhibitor carfilzomib is showing noteworthy response rates and low levels of adverse side effects among multiple myeloma patients in a phase II clinical trial, researchers reported at the 51st Annual Meeting of the American Society of Hematology. The updated data from the 17-site study focuses on patients with relapsed or resistant multiple myeloma who have received one to three prior therapies, but not the drug bortezomib, the original proteasome inhibitor. "These findings are truly an advance for patients with multiple myeloma," said Michael Wang, M... 
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