High-Resolution Comparison Of Methylation 'Bookmarks' Across Species And Individuals

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Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of Southern California (USC) have published the first quantitative evidence supporting the notion that the genome-wide "bookmarking" of DNA with methyl molecules - a process called methylation - and the underlying DNA sequences corresponding with these marks, have co-evolved in a kind of molecular slow-dance over the 6 million years since humans and chimps diverged from a common ancestor. The team's findings in some ways defy the conventional understanding of how methylation and related processes work...
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