Yes, as long as it uses the GSM North American standard that AT&T operates on. If the phone was purchased unlocked or from AT&T, then the device will automatically function properly. If it was purchased T-Mobile, then you'll need unlock the smartphone before you use it with AT&T, but even then the phone will only operate over AT&T's slower Edge network (not 3G). If the phone was purchased from Verizon, Sprint, or any other American carrier, the phone will not accept a sim card.