New research in the Journal of General Physiology helps explain how the body's "flight-or-fight" response is mediated. The study, which may provide new answers to the question of how the heart pacemaker - the sinoatrial (SA) node - is regulated, appeared online on August 16. When the body goes into "flight-or-flight" response as a reaction to stress, the increased firing rate of the SA node increases the heart rate and cardiac output to deliver more oxygen and nutrients to peripheral tissues, especially skeletal muscles...

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