Could drugs that block the body's system for repairing damage to the genetic material DNA become a boon to health? As unlikely as it may seem, those compounds are sparking optimism as potential treatments for ovarian and breast cancers driven by a mutation in BRCA, a gene that made headlines when actress Angelina Jolie revealed she carries the mutation. The compounds, termed PARP inhibitors, are the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly news magazine of the American Chemical Society, the world's largest scientific society...
More...
More...