Hepatitis A virus (HAV) is an epidemiologically important virus with a worldwide distribution and causes acute hepatitis in humans. Acute HAV superinfection causes severe liver disease, acute liver failure and even higher mortality rates in patients with underlying chronic liver disease (CLD). Numerous studies have identified CLD as a risk factor for fulminant hepatitis and death from acute HAV infection. A research article published in the World Journal of Gastroenterology addresses this question...
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