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Health and Fitness
The P53 Family: New Book Reviews Research On The 'Guardian Of The Genome'
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<blockquote data-quote="tD33NAt" data-source="post: 2214105" data-attributes="member: 124445"><p>The p53 tumor suppressor gene, the "guardian of the genome," protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of proteins that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy. A new book from Cold Spring Harbor Laboratory Press, The p53 Family, provides a comprehensive review of the functions of the p53 family. It was edited by Arnold Levine and David Lane, who independently discovered p53 about 30 years ago...<a href="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/0/da" target="_blank"><img src="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/0/di" alt="" class="fr-fic fr-dii fr-draggable " data-size="" style="" /></a></p><p><a href="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/1/da" target="_blank"><img src="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/1/di" alt="" class="fr-fic fr-dii fr-draggable " data-size="" style="" /></a></p><p></p><p><img src="http://feeds.feedburner.com/~r/mnt/healthnews/~4/eGuZsS_eSY4" alt="" class="fr-fic fr-dii fr-draggable " data-size="" style="" /></p><p></p><p><a href="http://feedproxy.google.com/~r/mnt/healthnews/~3/eGuZsS_eSY4/3Fms" target="_blank">More...</a></p></blockquote><p></p>
[QUOTE="tD33NAt, post: 2214105, member: 124445"] The p53 tumor suppressor gene, the "guardian of the genome," protects cells against genotoxic stress but is mutated in many cancers. It encodes one of a family of proteins that regulate cell proliferation, differentiation, senescence, and cell death. Mutations in p53 allow cells to escape normal growth controls and thereby contribute to tumor malignancy. A new book from Cold Spring Harbor Laboratory Press, The p53 Family, provides a comprehensive review of the functions of the p53 family. It was edited by Arnold Levine and David Lane, who independently discovered p53 about 30 years ago...[URL="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/0/da"][IMG]http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/0/di[/IMG][/URL] [URL="http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/1/da"][IMG]http://feedads.g.doubleclick.net/~a/BlW4PrSQsdgCKCyVkAyP34CDeQ4/1/di[/IMG][/URL] [IMG]http://feeds.feedburner.com/~r/mnt/healthnews/~4/eGuZsS_eSY4[/IMG] [url=http://feedproxy.google.com/~r/mnt/healthnews/~3/eGuZsS_eSY4/3Fms]More...[/url] [/QUOTE]
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