UC Davis investigators have found new evidence that a promising type of stem cell now being considered for a variety of disease therapies is very similar to the type of cells that give rise to cancer. The findings suggest that although the cells -- known as induced pluripotent stem cells (iPSCs)...
In the first study of its kind, a research team led by Mount Sinai School of Medicine and Albert Einstein College of Medicine of Yeshiva University discovered 12 genetic markers associated with the development of erectile dysfunction (ED) in prostate cancer patients who were treated with...
UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function...
People who carry a "G" instead of an "A" at a specific spot in their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, a Mayo Clinic and University of California, San Francisco study has found. The findings, published online in the journal Nature...
Cleveland Clinic researchers have discovered that a naturally occurring molecule may play a role in preventing plaque buildup inside arteries, possibly leading to new plaque-fighting drugs and improved screening of patients at risk of developing atherosclerosis. Sometimes called hardening or...
If you're concerned about losing your hearing because of noise exposure (earbud deafness syndrome), a new discovery published online in the FASEB Journal offers some hope. That's because scientists from Germany and Canada show that the protein, AMPK, which protects cells during a lack of energy...
In what could be a breakthrough in the practical application of epigenetic science, U.K. scientists used human tissue samples to discover that those with osteoarthritis have a signature epigenetic change (DNA methylation) responsible for switching on and off a gene that produces a destructive...
Researchers and doctors at the North Shore-LIJ Health System and the Feinstein Institute for Medical Research have discovered a potential explanation for why breast cancer is not experienced the same way with African American and Caucasian patients. This data was presented at the 2012 American...
Scientists Have Discovered A "Switch" In The Hepatitis C Virus Which Could Be Used As
Hepatitis C affects more than 170 million people worldwide, but current combination treatment is only effective against a limited range of this naturally highly variable virus. However, according to new...
My daughter turned 3 yesterday and has had the same Pediarician since birth and has been to all her well check and a few sick visits. She recently went for a evaluation for a speech delay at another hospital, while she was there another Peditrician did a physical and heard a heart murmur, she...
My daughter turned 3 yesterday and has had the same Pediarician since birth and has been to all her well check and a few sick visits. She recently went for a evaluation for a speech delay at another hospital, while she was there another Peditrician did a physical and heard a heart murmur, she...
Researchers at the University of Leeds have found a previously unknown mechanism through which pain is signalled by nerve cells - a discovery that could explain the current failings in the drug development process for painkillers and which may offer opportunities for a new approach...
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Alterations to the "on-off" switches of genes occur early in the development of prostate cancer and could be used as biomarkers to detect the disease months or even years earlier than current approaches, a Mayo Clinic study has found. These biomarkers - known as DNA methylation profiles - also...
C5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. This is what a study in The American Journal of Human Genetics...
Research on the fungus that ranks as one cause of dandruff - the embarrassing nuisance that, by some accounts, afflicts half of humanity - is pointing scientists toward a much-needed new treatment for the condition's flaking and itching. The advance is the topic of a report in ACS' Journal of...
A new approach to investigating hard-to-find chromosomal abnormalities has identified 33 genes associated with autism and related disorders, 22 for the first time. Several of these genes also appear to be altered in different ways in individuals with psychiatric disorders such as schizophrenia...
Researchers at the Perinatology Research Branch of the National Institutes of Health, located at the Wayne State University School of Medicine and the Detroit Medical Center, have demonstrated that a nanotechnology-based drug treatment in newborn rabbits with cerebral palsy (CP) enabled dramatic...
Two Massachusetts General Hospital (MGH)-based research teams, along with a group from the University of California at San Diego, have discovered that animals have a previously unknown system for detecting and responding to pathogens and toxins. In three papers published in the journals Cell and...
The hormone estrogen may help promote lung cancer - including compounding the effects of tobacco smoke on the disease - pointing towards potential new therapies that target the hormone metabolism, according to new research presented at the AACR Annual Meeting 2012 by scientists at Fox Chase...
Angiogenesis, the growth of new blood vessels, is a complex process during which different signalling proteins interact with each other in a highly coordinated fashion. The growth factor VEGF and the Notch signalling pathway both play important roles in this process. VEGF promotes vessel growth...