Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according to a study published online by the journal AIDS, official journal of...
On Thursday, a panel of outside experts that advises the US Food and Drug Administration (FDA) voted to support approval of the daily pill Truvada to prevent HIV in healthy people. The FDA is not obliged to follow the advice of its Antiviral Drugs Advisory Committee, but should it do so, then...
A once-a-day pill to help prevent HIV infection could significantly reduce the spread of AIDS, but only makes economic sense if used in select, high-risk groups, Stanford University researchers conclude in a new study. The researchers looked at the cost-effectiveness of the combination drug...
IRMA (International Rectal Microbicide Advocates) will release "On the Map: Ensuring Africa's Place in Rectal Microbicide Research and Advocacy" at a special evening reception at the international Microbicides 2012 conference at the Sydney Convention and Exhibition Center...
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Expanding on previous research providing proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers have now demonstrated that these cells can actually attack HIV-infected cells in a living organism. The study, published in the...
For the first time, US scientists have shown that HIV-fighting cells engineered from human stem cells can suppress the virus in living human tissue in mice. The team, from UCLA in Los Angeles, California, had already shown in principle that it was possible to create cells that seek out and...
Researchers have gained important clues about immune system responses that could play a role in protecting people from HIV infection in follow-up studies from the world's largest HIV vaccine trial to date. Results from laboratory studies based on the trial were published in the New England...
Women who have been infected by two different strains of HIV from two different sexual partners - a condition known as HIV superinfection - have more potent antibody responses that block the replication of the virus compared to women who've only been infected once. These findings, by researchers...
Circumcision has been shown to lower the risk of HIV transmission and infection in Africa. Now, a new device known as the PrePex enables circumcision to be performed without surgery or any blood loss, by nurses, who don't need extensive training to use the apparatus. The Rwandan Government has...
In eastern and southern Africa, expanding voluntary medical male circumcision (VMMC) for preventing HIV can help stem the spread of the disease at an individual, community and population level. In addition, VMMC can lead to significant expenditure savings for nations, according to a collection...
As World AIDS Day approaches, there are several encouraging statistics to celebrate: The UN says that world HIV/AIDS-related deaths have fallen 21% since their peak in 2005. The cost of treatment has decreased steadily in recent years. And plenty more statistics point to overwhelmingly positive...
The Children's Hospital of Philadelphia announced today that it will receive funding through Grand Challenges Explorations, an initiative created by the Bill & Melinda Gates Foundation that enables researchers worldwide to test unorthodox ideas that address persistent health and development...
Last week I shared a couple cigarettes and a couple joints with an uncle of someone I know. He looked looked unhealthy, had only 2 teeth, and used a wheel chair. When I asked him why he was in a wheel chair he completely avoided the question and would not answer. I am wondering if there mite be...
I've never personally known a single hetero male who's contracted HIV via tradional vaginal sex. Blood and semen are where the HIV virus is concentrared - not vaginal fluids. This explains why women are at a higher risk of contraction than men. And why homosexuals and those who share syringes...
Removing cholesterol from HIV's membrane stops it damaging the immune system, bringing the idea of a vaccine that uses this way of making an inactive virus a step closer. You can read how scientists at Imperial College London and Johns Hopkins University and colleagues came to these...
I am getting checked for STD's soon as I had unprotected sex many times with my ex boyfriend. But I remember when we first had sex I got quite ill (he also was ill) with a sore throat, cold, muscle ache and I read that it is a sign of HIV. Although this was in winter and it probably is just a...
The human body can produce powerful antibodies that shield cells in the laboratory against infection by an array of HIV strains. In people, however, recent research shows that these broadly neutralizing antibodies are not produced in an efficient or timely enough fashion in HIV-infected...