An anime with a strong female lead?

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AjaliqueChapman

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I'm looking for an anime with a strong female lead. I would prefer an anime like to aru kagaku no railgun. Some comedy and some action and a little tears now and then lol if you would please give me your top 5 anime that you can think of I would be really grateful! If you can't come up with any then I would also accept your top 5 overall anime as long as it's not bleach or naruto or code geas or something that everyone has seen lol also can you stick to some of the newer anime so 2008 and above. Please and thank you.
 
Claymore
Silent Mobius
Shakugan no Shana
Saber Marionette
Slayers
Devil Hunter Yohko
Vampire Princes Miyu
Mai-Hime, Mai-Otome
Devil Woman
Blood+
CCSakura
Elfen Lied
Ghost in the Shell
 
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