With my frogs/lizards, I always take them out while I clean it to make sure that they don't get out as I am cleaning it (I have front-opening cages and frogs that stick to the side of the cage). I rearrange the items, as well, to ensure proper "environmental enrichment". After rearranging the items, they always explore the "new" area and most seem happy to do so. Later on, they usually seem to find the same old spot that they used to hang out in all the time. Even with my most shy frogs, they don't seem to stress out once they are back in their cage, even with the rearranged items. With beardies, they usually don't stress out, period. Most would like the change.