UroToday.com - Randomized three-dimensional conformal radiotherapy dose escalation studies have consistently shown improved biochemical control rates for prostate cancer. This benefit was associated with the problem of increased rectal toxicity. The increasing implementation of image-guided radiotherapy (IGRT) allows a reduction of safety margins around the clinical target volume (CTV). Thus, the same or improved local tumour control with lower rectal toxicity due to reduced rectal volume within the target volume can be expected...
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