Help, I have sick fish. I have a 50 gallon tank with 3 blood parrot

SherriH

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cichlids and one large Pleco.? About two weeks ago I did a water change, about 50%. I now realize that was too much but now my fish are lethargic and rubbing themselves on the rocks. I have one black fish and he has a white spot on his fin. I had my water tested and they said my nitrates were high. They gave me Jungle Lifeguard all in one treatment. Will this hurt my pleco? What do I do to make my fish better?
The white spot looks like cotton
 
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