Having charted the occurrence of a common chemical change that takes place while stem cells decide their fates and progress from precursor to progeny, a Johns Hopkins-led team of scientists has produced the first-ever epigenetic landscape map for tissue differentiation. The details of this collaborative study between Johns Hopkins, Stanford and Harvard appear in the early online publication of Nature. The researchers, using blood-forming stem cells from mice, focused their investigation specifically on an epigenetic mark known as methylation...

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