IMMUNOLOGY: Context, context, context: all important for the immune function of NKT cells A therapeutic approach to harnessing immune cells known as NKT cells, which have potent immunomodulatory properties, is currently being tested in cancer patients in phase I clinical trials. However, initial results suggest that the approach will need to be modified if clinical outcomes are to be maximized. Rational modification of the approach requires increased understanding of the molecules that regulate NKT cell activation in vivo... 
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