In draft guidance published today (26 August 2010) NICE has recommended two treatments for multiple myeloma. Thalidomide (Thalidomide, Celgene) in combination with an alkylating agent and a corticosteroid is recommended for the first-line treatment of multiple myeloma in people for whom high-dose chemotherapy with stem cell transplantation is considered inappropriate. Bortezomib (Velcade, Janssen-Cilag) in combination with an alkylating agent and a corticosteroid is recommended as a treatment option if the person is unable to tolerate or has contraindications to thalidomide... 
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