I like The Joe Rogan Experience, half the time it's comics talking, other times it's fighters. A few weeks back he interviewed Dana White and it was brilliant!
Another vote for Radio 4, educate your mind, Joe Rogan can go.... (I better not finish that sentence) I used to spend a lot of time searching for stuff through Google Reader, bit of a shock that they are shelving it, with Wave boohoo
I've used Juice but that was a loooooong time ago now. Might consider going down that avenue again since I also have an mp3 player and hardly anyone around when I'm at work so easily bored
the joe rogan experince is the daddy don't let anyone tell you other wise, Neil Deggrasi Tyson, Shane Smith (multiple the most recent is not great), Enson Inoue, Chael Sonnen and Bas Rutten are good starting points. I also highly recommend dan carlins hardcore histories.
I only really have time to keep up with two podcasts, and I recommend them both: Skeptic's Guide to the Universe (for all my rational, logical needs), and Inside BJJ for my martial Arts needs!
Desert Island discs
Skeptics guide to the universe
Kermode and Mayo film reviews (Hello to Jason Issacs)
Richard Herring's Leicester square Theatre podcast (RHLSTP!)