UroToday.com - Endocrine treatment (ET), which interrupts testosterone regulation of the prostate tumor, is the cornerstone treatment for men with locally advanced or metastatic prostate cancer. A number of metabolic side-effects have been reported including increased body weight, insulin resistance, dyslipidemia, and hyperglycemia. One of the more recently investigated side-effects of ET is the increased risk of heart disease which is believed to be due to a reduced cardio-protective effect of testosterone...
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