What are the saddest films you've seen?

[NeonValium]

And yes, I mean anything from sad, depressing to out right tear-jerker.

Here's my list:
I Am Sam
Return To Paradise
Stand By Me
Requiem For A Dream
Edward Scissorhands
Marley & Me
Highway
Donnie Darko
Eternal Sunshine of the Spotless Mind
Real Time