Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins = known as Src = leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature...
Women with small early breast cancers may have a better chance of survival if they have lumpectomy plus radiation therapy than mastectomy, according to a new analysis due to be published early online in the journal Cancer this week. Although they did not determine why women who had mastectomy...
Patients with HER2-positive breast cancer being treated with anti-HER2 therapy may be able to prevent or delay resistance to the therapy with the addition of a phosphatidylinositol-3 kinase inhibitor to their treatment regimens. The data, published in Cancer Research, a journal of the American...
A new study from Wake Forest Baptist Medical Center is the first to report that high blood calcium levels might predict ovarian cancer, the most fatal of the gynecologic cancers. Lead author Gary G. Schwartz, Ph.D., a cancer epidemiologist at Wake Forest Baptist, and colleague, Halcyon G...
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the stable, epigenetic "marks" that sit on the nuclear DNA of cancer cells and...
Analysis of 2 Years of Additional Data on Dutasteride Treatment Reported in The Journal of Urology® The four-year REDUCE (REduction by DUtasteride of prostate Cancer Events) clinical study evaluated prostate cancer risk reduction in men taking dutasteride, a 5-alpha-reductase inhibitor (5ARI)...
Celegene Corp's drug Abraxane (paclitaxel protein-bound particles for injectable suspension) was found to be effective at improving overall survival among pancreatic cancer patients when combined with chemotherapy, according to results from the drug's phase III clinical trial. Even though...
I used to sign a ton of petitions, but then I realized I was getting about 8 million more in my inbox as a result. So, I unsubscribed to most of the websites that sent me requests to sign and only left a couple with my email address. Once in a while, I still receive a few petitions, and this was...
My mother was diagnosed with lung cancer in May 2012. She has been doing remarkably well all things considering. However she does have those really down days. So i was just wondering if anyone had any suggestions of humor for her on those down days. It could be a song, a book, a really funny...
A combination of the drugs pazopanib and paclitaxel shows promise in slowing anaplastic thyroid cancer (ATC), according to a Mayo Clinic-led study published in the journal Science Translational Medicine. The two drugs together resulted in greater anti-cancer activity in ATC than either drug...
I don't know why everybody's reporting on the new cancer rates report that came out yesterday like it isn't totally terrifying. The massive study comes from the American Cancer Society, the Centers for Disease Control and Prevention, the National Cancer Institute and the North American...
Fox Chase Cancer Center, a National Cancer Institute-designated Comprehensive Cancer Center, is now offering patients with advanced cancer a cutting-edge clinical test that will provide them with a unique blueprint of their cancer genes. The new clinical test, known as CancerCode-45TM, evaluates...
Medicare is putting out about as much money for screening breast cancer as it does treating it, claims a new study in JAMA Internal Medicine. Screening expenses for breast cancer in the Medicare program reached over $1 billion per year in the fee-for-service program during 2006 to 2007 with...
Pioneering research presented at the Fertility 2013 conference recently shows that a large proportion of male cancer patients are missing out on appropriate fertility advice. Sperm banking is routinely recommended for all men diagnosed with cancer who are at risk of long-term infertility, caused...
In order to study the effectiveness or cost effectiveness of treatments for recurrent cancer, you first have to discover the patients in medical databases who have recurrent cancer. Generally studies do this with billing or treatment codes - certain codes should identify who does and does not...
A small percentage of men in a prostate cancer study complained that their penis seemed shorter following treatment, with some saying that it interfered with intimate relationships and caused them to regret the type of treatment they chose. Complaints were more common in men treated with radical...
Obese, postmenopausal women are at greater risk for developing breast cancer and their cancers tend to be more aggressive than those in lean counterparts. A University of Colorado Cancer Center study published in the December issue of the journal Cancer Research shows how this risk might be...
As many as 50 percent of all human protein-coding genes are regulated by microRNA (miRNA) molecules. While some miRNAs impact onset and progression of cancer, others can actually suppress the development of malignant tumors and are useful in cancer therapy. They can also serve as potential...
The lifetime risks of cancer from medical radiation may be overemphasized relative to more immediate health risks, according to a new study published online in the journal Radiology. Radiation exposure from computed tomography (CT) and other medical sources has drawn considerable media attention...
The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State College of Medicine. A motor protein that transports cargo within the cell, km23-1 is also involved in the movement or migration of cells. Migration is necessary for cancer to spread...