A new study has yielded some surprising news about breast cancer in the United States: namely, that mammograms are responsible for a rapid increase in breast cancer overdiagnosis. The study, published today in the New England Journal of Medicine, found that breast cancer was overdiagnosed in...
In a world-first, researchers from the Australian Centre for Nanomedicine at the University of New South Wales (UNSW) in Sydney have developed a nanoparticle that could improve the effectiveness of chemotherapy for neuroblastoma by a factor of five. Neuroblastoma is an aggressive childhood...
Medical physicists at Thomas Jefferson University and Jefferson's Kimmel Cancer Center are one step closer to bringing a new tumor-tracking technique into the clinic that delivers higher levels of radiation to moving tumors, while sparing healthy tissue in lung cancer patients. Evidence has...
Although patients may feel anxious waiting weeks from the time of their first doctor visit to evaluate their breast until they have breast cancer surgery, new findings from Fox Chase Cancer Center show that these waits are typical in the United States. Results were published in the Journal of...
Adding Avastin to the current standard of care for newly diagnosed aggressive brain cancer (glioblastoma multiforme, GBM) can significantly extend the time people live without their disease worsening, by 4.4 months (progression free survival of 10.6 months compared to 6.2 months with radiation...
There are 'insufficient specialists' to serve the UK's multidisciplinary lung cancer teams (LCMDTs) - and some healthcare professionals still hold a 'pessimistic and outdated' view of what can be achieved for patients - says a new, national report published today (20 November) by leading lung...
In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin. More than 1 million cases of skin cancer are...
Kancera reports results from a collaboration with Professor Hakan Mellstedts research group at Karolinska Institute showing that the survival of an aggressive type of human cancer cells from pancreatic cancer is ROR-1 dependent. The results provide further support for the Kancera ROR project...
The quality of a woman's social networks - the personal relationships that surround an individual - appears to be just as important as the size of her networks in predicting breast cancer survival, Kaiser Permanente scientists report in the current issue of Breast Cancer Research and Treatment...
Combining cancer medication with a drug for erectile dysfunction and one for heart transplants helped kill cancer cells and protected the heart from damage, in a study presented at the American Heart Association's Scientific Sessions 2012. For decades, doxorubicin has been a powerful...
Adding an angiogenesis inhibitor to treatment with a HER2-inhibiting drug could improve outcomes for patients with HER2-positive breast cancer who develop brain metastases. In their report published online in PNAS Plus, Massachusetts General Hospital (MGH) investigators report the first...
A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed that specific targeting of the protein with monoclonal antibodies reduced...
A malarial drug is showing promise in stopping breast cancer before it starts, Mason researchers are discovering during a clinical trial. "The bold long-term goal is a short-term oral treatment that prevents breast cancer by killing the precursor cells that initiate breast cancer," says Lance...
New research led by the University of Manchester in the UK has found a biomarker or molecular "flag" in women with breast cancer who do not repond, or who have become resistant, to treatment with the hormone drug tamoxifen. The researchers say their discovery will help doctors predict which...
Cancer survivors who self-identified as being lesbian, gay or bisexual were more than twice as likely as heterosexual cancer survivors to have participated in cancer clinical trials, according to data from a small study presented at the Fifth AACR Conference on The Science of Cancer Health...
Racial and ethnic disparities in breast tumor aggressiveness might be explained by social factors that influence the developing tumor and place those in disadvantaged groups at higher risk for aggressive breast cancer, according to data presented at the Fifth AACR Conference on The Science of...
It has long been known that breast density, or mammographic density, is a strong risk factor for breast cancer, and that estrogen and progestin hormone therapy increases dense breast tissue. Now, a study published in BioMed Central's open access journal Breast Cancer Research has identified...
Avastin, or Bevacizumab, has been shown to increase survival from bowel cancer in around ten to 15 per cent of patients, but it has been impossible to predict who will benefit. Avastin works by targeting and blocking the VEGF-A protein, two major forms of which are VEGF165 and VEGF165b. VEGF165...
Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined the association between reproductive risk factors - such as the number of...