New research published in the Journal of the National Cancer Institute has found that a popular class of diabetes drug increases people's risk of developing bladder cancer. According to researchers from the Perelman School of Medicine at the University of Pennsylvania, the drug that accounts...
Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New treatments specifically attacking cancer cells, but not normal ones, are...
According to a study published online in the Proceedings of the National Academy of Sciences, an FDA-approved anti-epileptic drug has been found to reverse memory loss in a mouse model of Alzheimer's disease . The study, conducted by researchers at the Gladstone Institutes, also found that the...
A study published in the online journal Hepatology reports a potential new NADPH oxidase (NOX) inhibitor therapy for liver fibrosis, a scarring process associated with chronic liver disease that can lead to loss of liver function. "While numerous studies have now demonstrated that advanced liver...
Conflict-of-interest statements made by physicians and scientists in their medical journal articles after they had been allegedly paid by pharmaceutical manufacturers as part of off-label marketing programs are often inadequate, highlighting the deficiencies in relying on author candidness and...
A new drug could aid in losing weight and keeping it off. The drug, described in the journal Cell Metabolism, increases sensitivity to the hormone leptin, a natural appetite suppressant found in the body. Although so far the new drug has only been tested on mice, the findings have implications...
By analyzing the waste using urinary biomarkers, researchers can reliably detect actual drug consumption in cities. A large group of scientists has for the first time conducted a comparative study of illegal drug consumption in 19 European cities based on wastewater analysis. The findings are...
TGF-β2 inhibitor has gained market exclusivity in the USA for a third aggressive cancer indication The biopharmaceutical company Antisense Pharma GmbH announces that the US Food and Drug Administration (FDA) has granted Orphan Drug designation for its investigational oncology antisense...
The oral DPP-4 inhibitor linagliptin has been declared safe and effective in reducing glucose levels for up to 102 weeks, either as a stand-alone treatment or in combination with other selected oral anti-diabetic drugs, according to extended trials of individuals with type 2 diabetes in 32...
Numerous studies have been conducted on the impacting factors for pregnancy outcomes in young women, yet so far, no study has established which of these factors are the most important and the impact of depression on pregnancy outcomes is particularly unclear...
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A "one-size-fits-all" new class of drugs that targets a particular type of brain inflammation is showing early promise for the treatment of Alzheimer's disease, Parkinson's disease, multiple sclerosis and traumatic brain injury. A pre-clinical study due to be published this week in the...
Breast cancer treatments such as Herceptin that target a marker called HER2 have dramatically improved outcomes for women with this type of cancer. But nearly half of these cancers are resistant to Herceptin from the start and almost all of them will eventually become resistant. Now, researchers...
Drugs used to treat Attention Deficit Hyperactivity Disorder (ADHD) do not appear to have long-term effects on the brain, according to new animal research from Wake Forest Baptist Medical Center. As many as five to seven percent of elementary school children are diagnosed with ADHD, a behavioral...
A team led by a physician-scientist at the University of Southern California (USC) has created an experimental drug that reduces brain damage and improves motor skills among stroke-afflicted rodents when given with federally approved clot-busting therapy. Clinical trials to test the safety of...
The FDA has finally*approved a new drug that prevents HIV infection. The medicine, Truvada, is a daily pill expected to be taken by people at a high-risk of becoming infected with HIV (gay and bisexual men usually, but the drug has been approved for all HIV-negative people). This is awesome news...
Ticagrelor, a blood-thinning drug approved by the FDA in 2011, should be considered along with older blood thinners clopidogrel and prasugrel for treating patients who are experiencing chest pain or some heart attacks, according to joint updated guidelines issued by the American Heart...
Participants in drug trials are often not fully informed about the effect of placebos, thereby undermining the process of "informed consent", concludes a new study published this week in the open access journal PLoS ONE. Placebos are used in randomized drug trials to act as a yardstick or...
The FDA just approved Belviq, the first weight loss drug to get their green light in 13 years. The agency claims that its safety standards were set high (because of weight loss drugs' sketchy history), but it's hard to shake the feeling that their approval was made in the best interest of public...
With its 15 years conference production and management experience, WTG introduces a leading pharma event "Early Drug Development Summit" in December 3rd-4th 2012 in Berlin, Germany. The Early Drug Development Summit brings early drug developers together to discuss maximising drug investments...
An ancient heart drug that's inspired the work of herbalists and poets for centuries may treat a condition that plagues millions of overstressed and overweight Americans today. Since the 13th century, the herb Foxglove has been used to cleanse wounds and its dried leaves were brewed by Native...