Prostate cancer patients with advanced tumors that have spread to bone have a poor chance of surviving. Patients with the disease may now live longer with a new line of radioisotope therapy, said researchers at the Society of Nuclear Medicine's 2012 Annual Meeting. The skeletal systemis the...
A three-drug treatment for the blood cancer multiple myeloma provided rapid, deep and potentially durable responses, researchers report online in Blood, the Journal of the American Society of Hematology, and at the American Society of Clinical Oncology's Annual Meeting in Chicago, IL, USA. The...
A new medication proved effective in slowing the spread of metastatic prostate cancer, while helping to maintain the quality of life, in patients with advanced disease. The phase 3 study was unblinded midway, allowing patients receiving the placebo to instead take the drug because of the...
Many pharmaceutical companies in a new survey are making progress in embracing the guiding principles of green chemistry, which seek to minimize the use of potentially hazardous substances in producing medications, reduce the generation of waste and operate in other environmentally friendly...
UCLA biochemists have designed specialized proteins that assemble themselves to form tiny molecular cages hundreds of times smaller than a single cell. The creation of these miniature structures may be the first step toward developing new methods of drug delivery or even designing artificial...
A Colorado School of Public Health researcher has found that laws designed to illuminate financial links between doctors and pharmaceutical companies have little or no effect on what drugs physicians prescribe. "If the policymakers who passed these measures were hoping for a deterrent effect...
If you can't walk into a store without buying something, help may be at hand. New research suggests that a drug designed to treat Alzheimer's disease can be used to successfully treat people who suffer from shopping addictions. More »
Conventional cancer treatments, such as chemotherapy and radiation can cause toxic side-effects. Now, researchers have discovered that a drug called thioridazine can successfully destroy cancer stem cells in humans without these effects. Mick Bhatia, lead researcher of the study and scientific...
US researchers have discovered that an already approved arthritis drug may offer a cheap, low-dose treatment for the amoebic infections that cause dysentery in humans worldwide. So far they have only tested the drug in lab and animal studies, but they have applied for approval to start...
Researchers at the University of Leeds have found a previously unknown mechanism through which pain is signalled by nerve cells - a discovery that could explain the current failings in the drug development process for painkillers and which may offer opportunities for a new approach...
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Acute ischemic stroke patients taking the blood thinner warfarin can be treated safely with the clot-busting drug tissue plasminogen activator (tPA), according to research presented at the American Heart Association's Quality of Care and Outcomes Research Scientific Sessions 2012. "Although it's...
A new study published in Science is shedding light on the molecular details of PARP-1, a DNA damage-detecting enzyme that when inhibited has been shown to be effective in fighting cancer and other diseases. The investigation led by John M. Pascal, Ph.D., an assistant professor in the Department...
The Pharmacovigilance Legislation Will Come into Effect in July As the European Medicines Agency's new PV (pharmacovigilance) Legislation implementation date of July 2012 approaches, US and European pharmaceutical and biotech companies need to ask themselves if they are ready for the changes...
Lorcaserin, an investigational obesity drug, was given a positive recommendation by the Endocrinologic and Metabolic Drugs Advisory Committee, which advises the Food and Drug Administration (FDA). The Committee voted 18 to 4 in favor, with one abstention, in advising the FDA whether to approve...
The smoking cessation drug varenicline significantly reduced alcohol consumption in a group of heavy-drinking smokers, in a study carried out by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco. "Alcohol abuse is a huge problem, and this...
Pharmaceutical drugs approved by the Food and Drug Administration (FDA) but later re-called from the market - such as the antidiabetic drug Avandia and pain-reliever Vioxx - were the impetus for an Institute of Medicine committee report, recommending that the FDA take proactive steps to continue...
Infants born to women who used the anti-HIV drug tenofovir as part of an anti-HIV drug regimen during pregnancy do not weigh less at birth and are not of shorter length than infants born to women who used anti-HIV drug regimens that do not include tenofovir during pregnancy, according to...
In a surveillance study of over 12 million bacteria, investigators at The George Washington University and Providence Hospital found E. coli antimicrobial resistance to ciprofloxacin, the most commonly prescribed antimicrobial for urinary tract infections in the U.S., increased over five-fold...
Why do some teenagers start smoking or experimenting with drugs - while others don't? In the largest imaging study of the human brain ever conducted - involving 1,896 14-year-olds - scientists have discovered a number of previously unknown networks that go a long way toward an answer...
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Here's a list of items at convenience store which may be hazardous to a person's health: egg salad sandwiches, anything from the "grill", and any kind of over-the-counter "all natural" single-serving*erectile dysfunction supplement which promises to turn men into a sexy, sexy studs. Why? Because...