Inflammatory breast cancer (IBC) is a very aggressive, often misunderstood type of cancer that is diagnosed more frequently in younger women compared with other types of breast cancer. The five-year survival rate is between 25 and 50 percent - significantly lower than the survival rate for other...
The journal Computers in Biology and Medicine has published an article on the new IT application BootstRatio, created by IDIBELL researchers. The application allows online statistical analysis of data from gene expression*. Researchers at the Human Molecular Genetics group at IDIBELL, led by...
An international team of scientists has created an innovative tool for teaching the fundamentals of epidemiology - the science of how infectious diseases move through a population. The team teaches a workshop annually in South Africa that helps epidemiologists improve the mathematical models...
Cardiomyopathy comprises a deterioration of the heart muscle that affects the organ's ability to efficiently pump blood through the body. Previously researchers have tied forms of the disease to the alternative splicing of titin, a giant protein that determines the structure and biomechanical...
In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The study is published in Nature on Thursday 29 March 2012. The team uncovered hundreds of associations between mutations...
In the past decade, scientists have made significant progress building the critical knowledge and infrastructure needed to identify and develop novel tuberculosis (TB) vaccine candidates and move the most promising ones into human clinical trials. The results of those trials, coupled with...
Researchers from the Department of Health Policy in the GW School of Public Health and Health Services have found that an increased "scope of practice" for advanced practice nurse practitioners is not associated with lower wages for primary care physicians, based on comparisons in states with...
Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies. The scientists discovered that blocking the activity of the enzyme IKK2, which helps activate the...
Wheat allergy? Gluten sensitivity? Celiac's diseases? Hypochondria? As awareness of gluten's potential ill effects grows, so do the number of people who think they might benefit from a gluten-free diet. To help clear up individual confusion, and help doctors with diagnoses,*an*international...
Researchers at the La Jolla Institute for Allergy & Immunology have proven - for the first time in human tissues - the specific immune system T cells which trigger the destruction of type 1 diabetes in the pancreas. The finding is an important advance that verifies in humans several important...
A malignancy-risk gene signature developed for breast cancer has been found to have predictive and prognostic value for patients with early stage non-small cell lung cancer. The advancement was made by researchers at Moffitt Cancer Center in Tampa, Fla., who published their study results in a...
Despite the numerous medical advances that happen every day, the infant mortality rate in the United States is still higher than most European countries. While experts believe this is closely linked to the growing rate of pre-term births, researchers are committed to finding ways to make labor...
The University of Kentucky Markey Cancer Center breast oncologist Dr. Suleiman Massarweh and his research team presented findings from their studies on relapse of breast cancer at the San Antonio Breast Cancer Symposium this month. The two studies aimed to characterize further risk factors for...
Working with genetically engineered mice, Johns Hopkins researchers have discovered that a gene (SIRT1) linked to slowing the aging process in cells also appears to dramatically delay the onset of Huntington's disease (HD) and slow the progression of the relentless neurodegenerative disorder. HD...
Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells which group together and are static- losing adhesion and moving towards a new site. This process, which is common to developing organisms, is very similar...
Medical researchers at the University of Alberta have created a deck of cards with conversation starters about sensitive and informational topics related to weight, that parents can use to guide their discussions when talking about their child's weight management with health professionals...
Development: How specific cells are generated in the spinal cord How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this...
Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause. The research (abstracts 261, 300, 434 and 597), to be...
How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. They found out that the matrix protein tenascin C has to be...