A research team led by St. Jude Children's Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma. Their work also settles a scientific debate by showing the cancer's cellular origins are as scrambled as the developmental pathways at work in the tumor. Unlike other cancers that resemble a particular type of cell, researchers showed that retinoblastoma is a hybrid cell with elements of at least three different cell types. Investigators made the discovery using a variety of techniques to study 52 tumors donated by patients...
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