Most of them have been fulfilled, there are still some to come. These are some that are currently being fulfilled in our time:
(Matthew 24:6-14) .*.*.YOU are going to hear of wars and reports of wars; see that YOU are not terrified. For these things must take place, but the end is not yet. 7*“For nation will rise against nation and kingdom against kingdom, and there will be food shortages and earthquakes in one place after another. 8*All these things are a beginning of pangs of distress. 9*“Then people will deliver YOU up to tribulation and will kill YOU, and YOU will be objects of hatred by all the nations on account of my name. 10*Then, also, many will be stumbled and will betray one another and will hate one another. 11*And many false prophets will arise and mislead many; 12*and because of the increasing of lawlessness the love of the greater number will cool off. 13*But he that has endured to the end is the one that will be saved. 14*And this good news of the kingdom will be preached in all the inhabited earth for a witness to all the nations; and then the end will come.
(2 Timothy 3:1-5) .*.*.But know this, that in the last days critical times hard to deal with will be here. 2*For men will be lovers of themselves, lovers of money, self-assuming, haughty, blasphemers, disobedient to parents, unthankful, disloyal, 3*having no natural affection, not open to any agreement, slanderers, without self-control, fierce, without love of goodness, 4*betrayers, headstrong, puffed up [with pride], lovers of pleasures rather than lovers of God, 5*having a form of godly devotion but proving false to its power; and from these turn away.
In Matthew 24 it continues to show that there will be a Great Tribulation
(Matthew 24:21) .*.*.for then there will be great tribulation such as has not occurred since the world’s beginning until now, no, nor will occur again.
this is the destruction of all false religion (info is in Revelation), then the destruction of all political systems (Daniel 2:44), then all who are connected with either of these two will be destroyed along with Satan and his demons (Revelation 20).
Jesus started to reign in heaven in 1914 (this can be proved mathematically using prophesies from Daniel 9), it's interesting that since World War 1 the events in Matthew 24 and 2 Timothy 3 have rapidly increased. We live in the most unstable period of human history - it's global, not isolated.
Don't be afraid - in Luke 21 where the prophesy in Matthew 24 is repeated there is some additional information about when the Great Tribulation starts:
(Luke 21:28) .*.*.But as these things start to occur, raise yourselves erect and lift YOUR heads up, because YOUR deliverance is getting near.”
(Revelation 7:9-10) .*.*.After these things I saw, and, look! a great crowd, which no man was able to number, out of all nations and tribes and peoples and tongues, standing before the throne and before the Lamb, dressed in white robes; and there were palm branches in their hands. 10*And they keep on crying with a loud voice, saying: “Salvation [we owe] to our God, who is seated on the throne, and to the Lamb.”
(Revelation 7:14) .*.*.So right away I said to him: “My lord, you are the one that knows.” And he said to me: “These are the ones that come out of the great tribulation, and they have washed their robes and made them white in the blood of the Lamb.
Jesus is the one who will lead the destruction of false religion, political systems and the destruction of all those who are causing pain and suffering on the earth (also info in Revelation 6)