How do you turn off the file open warning in windows 7 (screenshot)?

I

Intel+nVidiat

New member
this comes whenever i want to open a program like paint or even the start up programs:

http://i329.photobucket.com/albums/l362/kuklor/Untitled.png

I already turned UAC off.
I did AVG, Avast and Spybot S+D search.
 
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