is there any reason why I can't use antigenicity prediction software to generate...

cathyt

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...peptides for screening serum? My examiner says this type of software is usually used for designing peptides to immunize and generate antibodies, and "never used" for screening serum (for antibodies generated by DNA immunization), and that therefore this approach is "patently wrong". Can anyone explain why it is wrong, or point me in the direction of a published instance of this use? Many thanks!
 
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