I am looking for films with a specific plot, one set on a spaceship or in deep space, where the crew, or someone, has gone mad and jeopardises the mission.
Alien could be a good one. No one really goes 'mad', but the andriod jeopardizes the lives of the marines by following orders that they are not aware of. If you want more information on the movie I would be happy to give more detail, but judging by the question I assume you would know this movie.